Israel Vázquez has five losses against four opponents on his boxing record. For a list of Vázquez's best fights, refer to "Best fights of Israel Vázquez".
On May 22, 2010 Israel Vázquez faced off against Rafael Márquez in a featherweight bout at age 32. He was coming in with a record of 44-5 (32), and Márquez was 35 years old and with a record of 38-5 (34). Vázquez lost the fight via 3rd-round KO.
On March 3, 2007 Israel Vázquez met Rafael Márquez in a super-bantamweight (WBC, The Ring) world-title defense fight. Vázquez was 29 years old and with a record of 41-4 (30), and Márquez was 31 years old and with a record of 36-3 (32). Vázquez lost the fight via 7th-round retirement and lost the titles.
On May 17, 2002 Israel Vázquez fought Óscar Larios in a super-bantamweight world-title fight for the WBC title. Vázquez was 24 years old and with a record of 32-3 (23), and Larios was 25 years old and with a record of 43-3-1 (30). Vázquez lost the fight via 12th-round TKO.
On March 27, 1999 Israel Vázquez faced off against Marcos Licona in a super-bantamweight bout at age 21. He was coming in with a record of 20-2 (15). Vázquez lost the fight via 12-round split decision.
On October 5, 1996 Israel Vázquez faced off against Ulises Flores at age 18. He was coming in with a record of 9-1 (8). Vázquez lost the fight via 1st-round TKO.