Guillermo Jones has three losses against three opponents on his boxing record. For a list of Jones's best fights, refer to "Best fights of Guillermo Jones".
On April 2, 2005 Guillermo Jones faced off against Steve Cunningham at age 32. He was coming in with a record of 31-3-2 (24), and Cunningham was 28 years old and with a record of 16-0 (9). Jones lost the fight via 10-round split decision.
On May 30, 1998 Guillermo Jones fought Laurent Boudouani in a super-welterweight world-title fight for Boudouani's WBA title. Jones was 26 years old and with a record of 22-2-1 (19). Jones lost the fight via 12-round split decision.
On September 27, 1997 Guillermo Jones faced off against David Noel in a super-welterweight bout at age 25. He was coming in with a record of 21-1 (18). Jones lost the fight via 2nd-round KO.