Amanda Serrano has four losses against two opponents on her boxing record. For a list of Serrano's best fights, refer to "Best fights of Amanda Serrano".
On July 11, 2025 Amanda Serrano fought Katie Taylor in a super-lightweight world-title fight for Taylor's WBA, WBC, IBF, WBO and The Ring titles. Serrano was 36 years old and with a record of 47-4-1 (31), and Taylor was 39 years old and with a record of 24-1 (6). Serrano lost the fight via 10-round majority decision.
On November 15, 2024 Amanda Serrano fought Katie Taylor in a super-lightweight world-title fight for Taylor's WBA, WBC, IBF, WBO and The Ring titles. Serrano was 36 years old and with a record of 47-3-1 (31), and Taylor was 38 years old and with a record of 23-1 (6). Serrano lost the fight via 10-round unanimous decision.
On April 30, 2022 Amanda Serrano fought Katie Taylor in a lightweight world-title fight for Taylor's WBA, WBC, IBF, WBO and The Ring titles. Serrano was 33 years old and with a record of 42-2-1 (30), and Taylor was 35 years old and with a record of 20-0 (6). Serrano lost the fight via 10-round split decision.
On April 27, 2012 Amanda Serrano fought Frida Wallberg in a super-featherweight world-title fight for Wallberg's WBC title. Serrano was 23 years old and with a record of 14-1-1 (9), and Wallberg was 28 years old and with a record of 10-0 (2). Serrano lost the fight via 10-round unanimous decision.