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Ray Mancini had a total of five losses in his professional boxing career — four of them in title bouts and one in a non-title bout. He suffered his first loss against Alexis Argüello via 14th round TKO on October 3, 1981, which ended his 20-fight win streak. He has been stopped three times and lost two times via decision.
Greg Haugen, Héctor Camacho, Livingstone Bramble, and Alexis Argüello are the four boxers who have beaten Mancini.
This is the first loss in Ray Mancini's career. Mancini lost to Nicaraguan boxer Alexis Argüello via 14th round TKO on . He was fighting for Argüello's lightweight WBC and The Ring titles, he was 20 years old with a record of 20-0. Argüello was 29 years old with a record of 67-5.
On Mancini lost to St. Kitts & Nevis boxer Livingstone Bramble via 14th round TKO. He was defending his lightweight WBA title, he was 23 years old with a record of 29-1. Bramble was also 23 years old, with a record of 20-1-1.
On Mancini lost to St. Kitts & Nevis boxer Livingstone Bramble in the rematch via 15 round unanimous decision. He was fighting for Bramble's lightweight WBA title, he was 23 years old with a record of 29-2. Bramble was 24 years old with a record of 22-1-1.
On Mancini lost to Puerto Rican boxer Héctor Camacho via 12 round split decision. He and Camacho were fighting for the vacant super-lightweight WBO title. He was 28 years old with a record of 29-3. Camacho was 26 years old with a record of 33-0.
On Mancini lost to Greg Haugen via 7th round TKO in a non-title bout. He was 31 years old with a record of 29-4. Haugen was also 31 years old, with a record of 29-4.