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Keith Holmes had a total of five losses in his professional boxing career — two of them in title bouts and three in non-title bouts. He suffered his first loss against Ronald Hammond via 6 round unanimous decision on July 20, 1990. He has never been stopped, all his losses came via decision.
Tito Mendoza, Roman Karmazin, Bernard Hopkins, Hacine Cherifi, and Ronald Hammond are the five boxers who have beaten Holmes.
This is the first loss in Keith Holmes' career. Holmes lost to Ronald Hammond via 6 round unanimous decision on in a non-title bout. He was 21 years old with a record of 7-0.
On Holmes lost to Hacine Cherifi via 12 round unanimous decision. He was defending his middleweight WBC title, he was 29 years old with a record of 31-1.
On Holmes lost to Bernard Hopkins via 12 round unanimous decision. He was defending his middleweight WBC title, he was 32 years old with a record of 36-2. Hopkins was 36 years old with a record of 38-2-1.
On Holmes lost to Russian boxer Roman Karmazin via 12 round majority decision in a non-title bout. He was 36 years old with a record of 39-3. Karmazin was 32 years old with a record of 32-1-1.
On Holmes lost to Tito Mendoza via 8 round unanimous decision in a non-title bout. He was 37 years old with a record of 40-4.