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José Luis Castillo had a total of 13 losses in his professional boxing career — four of them in title bouts and nine in non-title bouts. He suffered his first loss against César Soto via 2nd round TKO on July 9, 1993, which ended his 18-fight win streak. He has been stopped eight times and lost five times via decision.
Ruslan Provodnikov, Antwone Smith, Jorge Páez Jr., Alfonso Gómez, and Sebastián Luján are some of the boxers who have beaten Castillo.
This is the first loss in José Luis Castillo's career. Castillo lost to César Soto via 2nd round TKO on in a non-title bout. He was 19 years old with a record of 18-0.
On Castillo lost to Javier Jauregui via 10th round TKO in a non-title bout. He was 20 years old with a record of 20-1.
On Castillo lost to Javier Jauregui in a rematch via 10th round TKO in a non-title bout. He was 22 years old with a record of 24-2.
On Castillo lost to Julio Alvarez via 10th round TKO in a non-title bout. He was 24 years old with a record of 33-3.
On Castillo lost to American boxer Floyd Mayweather Jr. via 12 round unanimous decision. He was defending his lightweight WBC title, and fighting for the vacant The Ring title. He was 28 years old with a record of 45-4-1. Mayweather Jr. was 25 years old with a record of 27-0.
On Castillo lost to American boxer Floyd Mayweather Jr. in a rematch via 12 round unanimous decision. He was fighting for Mayweather Jr.'s lightweight WBC and The Ring titles, he was 28 years old with a record of 46-5-1. Mayweather Jr. was 25 years old with a record of 28-0.
On Castillo lost to American boxer Diego Corrales via 10th round TKO. He was defending his lightweight WBC and The Ring titles, and fighting for Corrales' lightweight WBO title, he was 31 years old with a record of 52-6-1. Corrales was 27 years old with a record of 39-2.
On Castillo lost to British boxer Ricky Hatton via 4th round KO. He was fighting for Hatton's super-lightweight The Ring title, he was 33 years old with a record of 55-7-1. Hatton was 28 years old with a record of 42-0.
On Castillo lost to Sebastián Luján via 10 round unanimous decision in a non-title bout. He was 34 years old with a record of 56-8-1.
On Castillo lost to fellow Mexican boxer Alfonso Gómez via 6th round RTD in a non-title bout. He was 36 years old with a record of 60-9-1. Gómez was 29 years old with a record of 21-4-2.
On Castillo lost to Jorge Páez Jr. via 12 round unanimous decision in a non-title bout. He was 37 years old with a record of 62-10-1.
On Castillo lost to Antwone Smith via 10 round unanimous decision in a non-title bout. He was 39 years old with a record of 64-11-1.
On Castillo lost to Russian boxer Ruslan Provodnikov via 5th round TKO in a non-title bout. He was 40 years old with a record of 66-12-1. Provodnikov was 30 years old with a record of 23-3.