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Jessie Vargas has had a total of four losses in his professional boxing career so far — one of them in a title bout and three in non-title bouts. He suffered his first loss against Timothy Bradley via 12 round unanimous decision on June 27, 2015, which ended his 26-fight win streak. He has been stopped once and lost three times via decision.
Liam Smith, Mikey Garcia, Manny Pacquiao, and Timothy Bradley are the four boxers who have beaten Vargas.
This is the first loss in Jessie Vargas' career. Vargas lost to Timothy Bradley via 12 round unanimous decision on in a non-title bout. He was 26 years old with a record of 26-0. Bradley was 31 years old with a record of 31-1-1.
On Vargas lost to Filipino boxer Manny Pacquiao via 12 round unanimous decision. He was defending his welterweight WBO title, he was 27 years old with a record of 27-1. Pacquiao was 37 years old with a record of 58-6-2.
On Vargas lost to Mikey Garcia via 12 round unanimous decision in a non-title bout. He was 30 years old with a record of 29-2-2. Garcia was 32 years old with a record of 39-1.
On Vargas lost to British boxer Liam Smith via 10th round TKO in a non-title bout. He was 32 years old with a record of 29-3-2. Smith was 33 years old with a record of 30-3-1.