Wilfredo Vázquez has nine losses against nine opponents on his boxing record. For a list of Vázquez's best fights, refer to "Best fights of Wilfredo Vázquez".
On June 16, 2000 Wilfredo Vázquez faced off against Juan Lazcano in a lightweight bout at age 39. He was coming in with a record of 52-9-2 (38), and Lazcano was 25 years old and with a record of 22-2-1 (16). Vázquez lost the fight via 9th-round TKO.
On April 18, 1998 Wilfredo Vázquez fought Naseem Hamed in a featherweight world-title fight for Hamed's WBO title. Vázquez was 37 years old and with a record of 50-8-2 (37), and Hamed was 24 years old and with a record of 29-0 (27). Vázquez lost the fight via 7th-round TKO.
On May 13, 1995 Wilfredo Vázquez met Antonio Cermeño in a super-bantamweight (WBA) world-title defense fight. Vázquez was 34 years old and with a record of 42-7-2 (32). Vázquez lost the fight via 12-round unanimous decision and lost the title.
On June 19, 1990 Wilfredo Vázquez faced off against Israel Contreras at age 29. He was coming in with a record of 28-6-2 (23). Vázquez lost the fight via 1st-round KO.
On August 1, 1988 Wilfredo Vázquez faced off against Raúl Pérez at age 27. He was coming in with a record of 26-5-2 (22). Vázquez lost the fight via 10-round unanimous decision.
On May 9, 1988 Wilfredo Vázquez met Khaokor Galaxy in a bantamweight (WBA) world-title defense fight. Vázquez was 27 years old and with a record of 26-4-2 (22). Vázquez lost the fight via 12-round split decision and lost the title.
On May 30, 1986 Wilfredo Vázquez faced off against Antonio Avelar at age 25. He was coming in with a record of 22-3-1 (18). Vázquez lost the fight via 8th-round TKO.
On February 8, 1986 Wilfredo Vázquez fought Miguel Lora in a bantamweight world-title fight for Lora's WBC title. Vázquez was 25 years old and with a record of 21-2-1 (17). Vázquez lost the fight via 12-round unanimous decision.
On January 29, 1981 Wilfredo Vázquez faced off against William Ramos at age 20. He was coming in with a record of 0-1 (0). Vázquez lost the fight via 4-round points decision.