Wilfredo Gómez has three losses against three opponents on his boxing record. For a list of Gómez's best fights, refer to "Best fights of Wilfredo Gómez".
On May 24, 1986 Wilfredo Gómez met Alfredo Layne in a super-featherweight (WBA, The Ring) world-title defense fight. Gómez was 29 years old and with a record of 42-3-1 (40). Gómez lost the fight via 9th-round TKO and lost the titles.
On December 8, 1984 Wilfredo Gómez met Azumah Nelson in a featherweight (WBC) world-title defense fight. Gómez was 28 years old and with a record of 41-2-1 (40), and Nelson was 26 years old and with a record of 19-1 (14). Gómez lost the fight via 11th-round KO and lost the title.
On August 21, 1981 Wilfredo Gómez fought Salvador Sánchez in a featherweight world-title fight for Sánchez' WBC title. Gómez was 24 years old and with a record of 32-1-1 (32), and Sánchez was 22 years old and with a record of 40-1-1 (30). Gómez lost the fight via 8th-round TKO.