Urbano Antillon has three losses against three opponents on his boxing record. For a list of Antillon's best fights, refer to "Best fights of Urbano Antillon".
On July 9, 2011 Urbano Antillon fought Brandon Rios in a lightweight world-title fight for Rios' WBA title. Antillon was 28 years old and with a record of 28-3 (20), and Rios was 25 years old and with a record of 27-0-1 (20). Antillon lost the fight via 3rd-round KO.
On December 4, 2010 Urbano Antillon fought Humberto Soto in a lightweight world-title fight for Soto's WBC title. Antillon was 28 years old and with a record of 28-2 (20), and Soto was 30 years old and with a record of 52-7-2 (32). Antillon lost the fight via 12-round unanimous decision.
On July 25, 2009 Urbano Antillon fought Miguel Acosta in a lightweight world-title fight for Acosta's WBA title. Antillon was 26 years old and with a record of 26-1 (19), and Acosta was 31 years old and with a record of 25-3-2 (19). Antillon lost the fight via 9th-round TKO.