Shane Mosley Jr. has four losses against four opponents on his boxing record. For a list of Mosley Jr.'s best fights, refer to "Best fights of Shane Mosley Jr.".
On May 29, 2021 Shane Mosley Jr. faced off against Jason Quigley in a middleweight bout at age 29. He was coming in with a record of 17-4 (10), and Quigley was 30 years old and with a record of 18-1 (14). Mosley Jr. lost the fight via 10-round majority decision.
On November 9, 2018 Shane Mosley Jr. faced off against Brandon Adams at age 26. He was coming in with a record of 13-3 (8), and Adams was 29 years old and with a record of 20-2 (13). Mosley Jr. lost the fight via 10-round unanimous decision.
On July 2, 2017 Shane Mosley Jr. faced off against David Toussaint at age 25. He was coming in with a record of 10-2 (7). Mosley Jr. lost the fight via 8-round split decision.
On September 20, 2014 Shane Mosley Jr. faced off against Marchristopher Adkins at age 22. He was coming in with a record of 2-1 (2). Mosley Jr. lost the fight via 4-round split decision.