Sergiy Derevyanchenko has six losses against six opponents on his boxing record. For a list of Derevyanchenko's best fights, refer to "Best fights of Sergiy Derevyanchenko".
On August 17, 2024 Sergiy Derevyanchenko faced off against Christian M'billi at age 38. He was coming in with a record of 15-6 (10), and M'billi was 29 years old and with a record of 27-0 (23). Derevyanchenko lost the fight via 10-round unanimous decision.
On June 10, 2023 Sergiy Derevyanchenko faced off against Jaime Munguía in a super-middleweight bout at age 37. He was coming in with a record of 14-5 (10), and Munguía was 26 years old and with a record of 41-0 (33). Derevyanchenko lost the fight via 12-round unanimous decision.
On December 5, 2021 Sergiy Derevyanchenko faced off against Carlos Adames at age 36. He was coming in with a record of 13-4 (10), and Adames was 27 years old and with a record of 20-1 (16). Derevyanchenko lost the fight via 10-round majority decision.
On September 26, 2020 Sergiy Derevyanchenko fought Jermall Charlo in a middleweight world-title fight for Charlo's WBC title. Derevyanchenko was 34 years old and with a record of 13-3 (10), and Charlo was 30 years old and with a record of 30-0 (22). Derevyanchenko lost the fight via 12-round unanimous decision.
On October 5, 2019 Sergiy Derevyanchenko fought Gennady Golovkin in a middleweight world-title fight for the IBF title. Derevyanchenko was 33 years old and with a record of 13-2 (10), and Golovkin was 37 years old and with a record of 39-1-1 (35). Derevyanchenko lost the fight via 12-round unanimous decision.
On October 27, 2018 Sergiy Derevyanchenko fought Daniel Jacobs in a middleweight world-title fight for the IBF title. Derevyanchenko was 32 years old and with a record of 12-1 (10), and Jacobs was 31 years old and with a record of 34-2 (29). Derevyanchenko lost the fight via 12-round split decision.