Sergio Martínez has three losses against three opponents on his boxing record. For a list of Martínez's best fights, refer to "Best fights of Sergio Martínez".
On June 7, 2014 Sergio Martínez met Miguel Cotto in a middleweight (WBC, The Ring) world-title defense fight. Martínez was 39 years old and with a record of 51-3-2 (28), and Cotto was 33 years old and with a record of 38-4 (31). Martínez lost the fight via 10th-round retirement and lost the titles.
On December 5, 2009 Sergio Martínez faced off against Paul Williams at age 34. He was coming in with a record of 44-2-2 (24), and Williams was 28 years old and with a record of 37-1 (27). Martínez lost the fight via 12-round majority decision.
On February 19, 2000 Sergio Martínez faced off against Antonio Margarito at age 24. He was coming in with a record of 16-1-1 (6), and Margarito was 21 years old and with a record of 20-3 (12). Martínez lost the fight via 7th-round TKO.