Sandy Ryan has three losses against two opponents on her boxing record. For a list of Ryan's best fights, refer to "Best fights of Sandy Ryan".
On March 29, 2025 Sandy Ryan fought Mikaela Mayer in a welterweight world-title fight for Mayer's WBO title. Ryan was 31 years old and with a record of 7-3-1 (3), and Mayer was 34 years old and with a record of 20-2 (5). Ryan lost the fight via 10-round unanimous decision.
On September 27, 2024 Sandy Ryan met Mikaela Mayer in a welterweight (WBO) world-title defense fight. Ryan was 31 years old and with a record of 7-2-1 (3), and Mayer was 34 years old and with a record of 19-2 (5). Ryan lost the fight via 10-round majority decision and lost the title.
On March 12, 2022 Sandy Ryan faced off against Erica Farias at age 28. She was coming in with a record of 3-1 (2), and Farias was 37 years old and with a record of 26-5 (10). Ryan lost the fight via 10-round split decision.
