Here is a list of Vargas's best fights. For a list of Vargas's losses, refer to "Samuel Vargas Losses".
On March 18, 2017 Samuel Vargas faced off against Armando Robles in a welterweight bout at age 27. He was coming in with a record of 26-3-1 (13), and Robles was 39 years old and with a record of 31-5-2 (17). Vargas won the fight via 10-round unanimous decision.
On February 11, 2012 Samuel Vargas faced off against Manolis Plaitis in a welterweight bout at age 22. He was coming in with a record of 9-0-1 (3). Vargas stopped Manolis Plaitis via TKO.