Roman Karmazin has five losses against five opponents on his boxing record. For a list of Karmazin's best fights, refer to "Best fights of Roman Karmazin".
On October 7, 2011 Roman Karmazin faced off against Osumanu Adama in a middleweight bout at age 38. He was coming in with a record of 40-5-2 (26), and Adama was 30 years old and with a record of 19-2 (14). Karmazin lost the fight via 9th-round TKO.
On October 31, 2010 Roman Karmazin faced off against Daniel Geale in a middleweight bout at age 37. He was coming in with a record of 40-4-2 (26), and Geale was 29 years old and with a record of 23-1 (14). Karmazin lost the fight via 12th-round TKO.
On January 19, 2008 Roman Karmazin faced off against Alex Bunema in a super-welterweight bout at age 35. He was coming in with a record of 36-3-1 (23). Karmazin lost the fight via 10th-round TKO.
On July 8, 2006 Roman Karmazin met Cory Spinks in a super-welterweight (IBF) world-title defense fight. Karmazin was 33 years old and with a record of 34-2-1 (21), and Spinks was 28 years old and with a record of 34-3 (11). Karmazin lost the fight via 12-round majority decision and lost the title.
On July 12, 2002 Roman Karmazin fought Javier Castillejo in a super-welterweight world-title fight for Castillejo's WBC title. Karmazin was 29 years old and with a record of 29-1-1 (18), and Castillejo was 34 years old and with a record of 53-5 (36). Karmazin lost the fight via 12-round unanimous decision.