Oscar Larios has seven losses against six opponents on his boxing record. For a list of Larios's best fights, refer to "Best fights of Oscar Larios".
On March 12, 2009 Oscar Larios met Takahiro Ao in a featherweight (WBC) world-title defense fight. Larios was 32 years old and with a record of 63-7-1 (39), and Ao was 24 years old and with a record of 16-1-1 (8). Larios lost the fight via 12-round unanimous decision and lost the title.
On July 21, 2007 Oscar Larios fought Jorge Linares in a featherweight world-title fight for the WBC title. Larios was 30 years old and with a record of 59-6-1 (37), and Linares was 21 years old and with a record of 23-0 (14). Larios lost the fight via 10th-round TKO.
On July 2, 2006 Oscar Larios faced off against Manny Pacquiao in a super-featherweight bout at age 29. He was coming in with a record of 56-5-1 (36), and Pacquiao was 27 years old and with a record of 41-3-2 (32). Larios lost the fight via 12-round unanimous decision.
On December 3, 2005 Oscar Larios met Israel Vázquez in a super-bantamweight (WBC) world-title defense fight. Larios was 29 years old and with a record of 56-4-1 (36), and Vázquez was 27 years old and with a record of 38-3 (27). Larios lost the fight via 3rd-round TKO and lost the title.
On January 19, 2001 Oscar Larios fought Willie Jorrín in a super-bantamweight world-title fight for Jorrín's WBC title. Larios was 24 years old and with a record of 39-3-1 (30). Larios lost the fight via 12-round unanimous decision.
On October 23, 1998 Oscar Larios faced off against Agapito Sánchez in a super-bantamweight bout at age 21. He was coming in with a record of 29-2-1 (22), and Sánchez was 28 years old and with a record of 22-9-2 (11). Larios lost the fight via 5th-round TKO.
On April 12, 1997 Oscar Larios faced off against Israel Vázquez at age 20. He was coming in with a record of 20-1 (15), and Vázquez was 19 years old and with a record of 11-1 (10). Larios lost the fight via 1st-round KO.