Oleksandr Gvozdyk has two losses against two opponents on his boxing record. For a list of Gvozdyk's best fights, refer to "Best fights of Oleksandr Gvozdyk".
On June 15, 2024 Oleksandr Gvozdyk faced off against David Benavidez in a light-heavyweight bout at age 37. He was coming in with a record of 20-2 (16), and Benavidez was 27 years old and with a record of 28-0 (24). Gvozdyk lost the fight via 12-round unanimous decision.
On October 18, 2019 Oleksandr Gvozdyk, the WBC champion, met Artur Beterbiev, the IBF champion, in a light-heavyweight world-title unification fight. Gvozdyk was 32 years old and with a record of 17-1 (14), and Beterbiev was 34 years old and with a record of 14-0 (14). Gvozdyk lost the fight via 10th-round TKO and lost his title.