Nikki Adler has two losses against two opponents on her boxing record. For a list of Adler's best fights, refer to "Best fights of Nikki Adler".
On May 12, 2018 Nikki Adler fought Femke Hermans in a super-middleweight world-title fight for the WBO title. Adler was 31 years old and with a record of 16-2 (9), and Hermans was 28 years old and with a record of 6-1 (3). Adler lost the fight via 10-round unanimous decision.
On August 4, 2017 Nikki Adler, the WBC champion, met Claressa Shields, the IBF champion, in a super-middleweight world-title unification fight. Adler was 30 years old and with a record of 16-1 (9), and Shields was 22 years old and with a record of 3-0 (1). Adler lost the fight via 5th-round TKO and lost her title.