Muhammadkhuja Yaqubov has one loss against one opponent on his boxing record. For a list of Yaqubov's best fights, refer to "Best fights of Muhammadkhuja Yaqubov".
On March 18, 2022 Muhammadkhuja Yaqubov faced off against O'Shaquie Foster in a super-featherweight bout at age 26. He was coming in with a record of 18-1 (10), and Foster was 28 years old and with a record of 18-2 (11). Yaqubov lost the fight via 12-round unanimous decision.