Mark Anthony Barriga has two losses against two opponents on his boxing record. For a list of Barriga's best fights, refer to "Best fights of Mark Anthony Barriga".
On June 24, 2022 Mark Anthony Barriga fought Jonathan González in a light-flyweight world-title fight for González' WBO title. Barriga was 29 years old and with a record of 11-2 (2), and González was 31 years old and with a record of 25-3-1 (14). Barriga lost the fight via 12-round unanimous decision.
On December 1, 2018 Mark Anthony Barriga fought Carlos Licona in a strawweight world-title fight for the IBF title. Barriga was 25 years old and with a record of 9-1 (1). Barriga lost the fight via 12-round split decision.