Here is a list of Medina's best fights. For a list of Medina's losses, refer to "Manuel Medina Losses".
On July 12, 2003 Manuel Medina fought Scott Harrison in a featherweight world-title fight for Harrison's WBO title. Medina was 32 years old and with a record of 63-13 (30), and Harrison was 25 years old and with a record of 19-1-1 (9). Medina won the fight via 12-round split decision and is crowned the new featherweight world champion.
On July 8, 1990 Manuel Medina faced off against Steve Cruz at age 19. He was coming in with a record of 36-3 (19), and Cruz was 26 years old and with a record of 34-4 (19). Medina won the fight via 10-round unanimous decision.
On November 11, 2006 Manuel Medina faced off against Kevin Kelley at age 35. He was coming in with a record of 67-15 (32), and Kelley was 39 years old and with a record of 59-7-2 (39). Medina won the fight via 12-round majority decision.
On October 18, 1997 Manuel Medina faced off against Jose Ayala in a featherweight bout at age 26. He was coming in with a record of 54-10 (26). Medina stopped Jose Ayala via TKO.
On July 23, 2004 Manuel Medina faced off against Leonardo Resendiz in a super-featherweight bout at age 33. He was coming in with a record of 64-14 (31). Medina stopped Leonardo Resendiz via TKO.