Luke Keeler has three losses against two opponents on his boxing record. For a list of Keeler's best fights, refer to "Best fights of Luke Keeler".
On January 30, 2020 Luke Keeler fought Demetrius Andrade in a middleweight world-title fight for Andrade's WBO title. Keeler was 32 years old and with a record of 17-3-1 (5), and Andrade was 31 years old and with a record of 28-0 (17). Keeler lost the fight via 9th-round TKO.
On April 2, 2016 Luke Keeler faced off against Tom Doran in a middleweight bout at age 28. He was coming in with a record of 10-2 (5). Keeler lost the fight via 2nd-round TKO.
On February 14, 2015 Luke Keeler faced off against Tom Doran at age 27. He was coming in with a record of 8-1 (5). Keeler lost the fight via 3-round unanimous decision.