Larry Holmes has six losses against five opponents on his boxing record. For a list of Holmes's best fights, refer to "Best fights of Larry Holmes".
On January 24, 1997 Larry Holmes faced off against Brian Nielsen in a heavyweight bout at age 47. He was coming in with a record of 65-6 (42), and Nielsen was 31 years old and with a record of 31-0 (19). Holmes lost the fight via 12-round split decision.
On April 8, 1995 Larry Holmes fought Oliver McCall in a heavyweight world-title fight for McCall's WBC title. Holmes was 45 years old and with a record of 61-5 (40), and McCall was 29 years old and with a record of 25-5 (18). Holmes lost the fight via 12-round unanimous decision.
On June 19, 1992 Larry Holmes fought Evander Holyfield in a heavyweight world-title fight for Holyfield's WBA, WBC and IBF titles. Holmes was 42 years old and with a record of 54-4 (37), and Holyfield was 29 years old and with a record of 27-0 (22). Holmes lost the fight via 12-round unanimous decision.
On January 22, 1988 Larry Holmes fought Mike Tyson in a heavyweight world-title fight for Tyson's WBA, WBC and IBF titles. Holmes was 38 years old and with a record of 48-3 (34), and Tyson was 21 years old and with a record of 32-0 (28). Holmes lost the fight via 4th-round KO.
On April 19, 1986 Larry Holmes fought Michael Spinks in a heavyweight world-title fight for Spinks' IBF and The Ring titles. Holmes was 36 years old and with a record of 48-2 (34), and Spinks was 29 years old and with a record of 28-0 (19). Holmes lost the fight via 15-round split decision.
On September 21, 1985 Larry Holmes met Michael Spinks in a heavyweight (IBF, The Ring) world-title defense fight. Holmes was 35 years old and with a record of 48-1 (34), and Spinks was 29 years old and with a record of 27-0 (19). Holmes lost the fight via 15-round unanimous decision and lost the titles.