Here is a list of Casimero's best fights. For a list of Casimero's losses, refer to "John Riel Casimero Losses".
On February 10, 2012 John Riel Casimero fought Luis Alberto Lazarte in a light-flyweight world-title fight for Lazarte's IBF title. Casimero was 22 years old and with a record of 16-2 (10), and Lazarte was 40 years old and with a record of 49-10-2 (18). Casimero stopped Luis Alberto Lazarte via 10th-round TKO and is crowned the new light-flyweight world champion.
On April 20, 2019 John Riel Casimero fought Ricardo Espinoza Franco in a bantamweight world-title fight for Franco's WBO title. Casimero was 30 years old and with a record of 27-4 (18), and Franco was 21 years old and with a record of 23-2 (20). Casimero stopped Ricardo Espinoza Franco via 12th-round KO and is crowned the new bantamweight world champion.
On August 4, 2012 John Riel Casimero met Pedro Guevara in a light-flyweight (IBF) world-title defense fight. Casimero was 23 years old and with a record of 17-2 (10), and Guevara was 23 years old and with a record of 18-0-1 (13). Casimero won the fight via 12-round split decision and successfully defended his title.
On November 30, 2019 John Riel Casimero fought Zolani Tete in a bantamweight world-title fight for Tete's WBO title. Casimero was 30 years old and with a record of 29-4 (20), and Tete was 31 years old and with a record of 28-3 (21). Casimero stopped Zolani Tete via 3rd-round TKO and is crowned the new bantamweight world champion.
On August 14, 2021 John Riel Casimero met Guillermo Rigondeaux in a bantamweight (WBO) world-title defense fight. Casimero was 32 years old and with a record of 31-4 (21), and Rigondeaux was 40 years old and with a record of 20-1 (13). Casimero won the fight via 12-round split decision and successfully defended his title.
On December 3, 2022 John Riel Casimero faced off against Ryo Akaho in a super-bantamweight bout at age 33. He was coming in with a record of 32-4 (22), and Akaho was 36 years old and with a record of 39-2-2 (26). Casimero stopped Ryo Akaho via KO.
On September 26, 2020 John Riel Casimero met Duke Micah in a bantamweight (WBO) world-title defense fight. Casimero was 31 years old and with a record of 30-4 (21), and Micah was 29 years old and with a record of 24-0 (19). Casimero stopped Duke Micah via 3rd-round TKO and successfully defended his title.
On May 25, 2016 John Riel Casimero fought Amnat Ruenroeng in a flyweight world-title fight for Ruenroeng's IBF title. Casimero was 27 years old and with a record of 22-3 (14), and Ruenroeng was 36 years old and with a record of 17-0 (5). Casimero stopped Amnat Ruenroeng via 4th-round KO and is crowned the new flyweight world champion.
On October 13, 2024 John Riel Casimero faced off against Saul Sanchez in a super-bantamweight bout at age 35. He was coming in with a record of 34-4-1 (23), and Sanchez was 27 years old and with a record of 21-3 (12). Casimero stopped Saul Sanchez via TKO.
On October 3, 2008 John Riel Casimero faced off against Phaiboon Chumthong in a light-flyweight bout at age 19. He was coming in with a record of 11-0 (6). Casimero stopped Phaiboon Chumthong via TKO.