Here is a list of Guzmán's best fights. For a list of Guzmán's losses, refer to "Joan Guzmán Losses".
On November 17, 2007 Joan Guzmán met Humberto Soto in a super-featherweight (WBO) world-title defense fight. Guzmán was 31 years old and with a record of 28-0 (17), and Soto was 27 years old and with a record of 42-5-2 (27). Guzmán won the fight via 12-round unanimous decision and successfully defended his title.
On February 26, 2004 Joan Guzmán met Agapito Sánchez in a super-bantamweight (WBO) world-title defense fight. Guzmán was 27 years old and with a record of 21-0 (17), and Sánchez was 34 years old and with a record of 31-9-3 (16). Guzmán stopped Agapito Sánchez via 7th-round TKO and successfully defended his title.
On August 9, 2001 Joan Guzmán faced off against Héctor Ávila in a super-bantamweight bout at age 25. He was coming in with a record of 15-0 (13). Guzmán stopped Héctor Ávila via KO.
On February 1, 2000 Joan Guzmán faced off against Santiago Matos in a featherweight bout at age 23. He was coming in with a record of 10-0 (8). Guzmán stopped Santiago Matos via TKO.