Here is a list of Rodríguez's best fights.
On June 29, 2024 Jesse Rodríguez fought Juan Francisco Estrada in a super-flyweight world-title fight for Estrada's WBC and The Ring titles. Rodríguez was 24 years old and with a record of 20-0 (13), and Estrada was 34 years old and with a record of 44-3 (28). Rodríguez stopped Juan Francisco Estrada via 7th-round KO and is crowned the new super-flyweight world champion.
On February 5, 2022 Jesse Rodríguez fought Carlos Cuadras in a super-flyweight world-title fight for the WBC title. Rodríguez was 22 years old and with a record of 15-0 (10), and Cuadras was 33 years old and with a record of 39-4-1 (27). Rodríguez won the fight via 12-round unanimous decision and is crowned the new super-flyweight world champion.
On September 17, 2022 Jesse Rodríguez met Israel González in a super-flyweight (WBC) world-title defense fight. Rodríguez was 22 years old and with a record of 17-0 (11), and González was 25 years old and with a record of 28-4-1 (11). Rodríguez won the fight via 12-round unanimous decision and successfully defended his title.
On June 25, 2022 Jesse Rodríguez met Srisaket Sor Rungvisai in a super-flyweight (WBC) world-title defense fight. Rodríguez was 22 years old and with a record of 16-0 (11), and Rungvisai was 35 years old and with a record of 50-5-1 (43). Rodríguez stopped Srisaket Sor Rungvisai via 8th-round TKO and successfully defended his title.
On April 8, 2023 Jesse Rodríguez fought Cristian González in a flyweight world-title fight for the WBO title. Rodríguez was 23 years old and with a record of 18-0 (11), and González was 32 years old and with a record of 15-1 (5). Rodríguez won the fight via 12-round unanimous decision and is crowned the new flyweight world champion.
On November 9, 2024 Jesse Rodríguez met Pedro Guevara in a super-flyweight (WBC and The Ring) world-title defense fight. Rodríguez was 24 years old and with a record of 21-0 (14), and Guevara was 35 years old and with a record of 42-4-1 (22). Rodríguez stopped Pedro Guevara via 3rd-round TKO and successfully defended his titles.
On December 16, 2023 Jesse Rodríguez, the WBO champion, met Sunny Edwards, the IBF champion, in a flyweight world-title unification fight. Rodríguez was 23 years old and with a record of 19-0 (12), and Edwards was 27 years old and with a record of 20-0 (4). Rodríguez stopped Sunny Edwards via 9th-round retirement and is crowned the unified WBO and IBF champion.
On July 19, 2025 Jesse Rodríguez faced off against Phumelela Cafu at age 25. He was coming in with a record of 22-0 (15), and Cafu was 20 years old and with a record of 11-0-3 (8). Rodríguez stopped Phumelela Cafu via TKO.
