Jason Litzau has three losses against three opponents on his boxing record. For a list of Litzau's best fights, refer to "Best fights of Jason Litzau".
On June 18, 2011 Jason Litzau faced off against Adrien Broner in a super-featherweight bout at age 27. He was coming in with a record of 28-3 (21), and Broner was 21 years old and with a record of 20-0 (16). Litzau lost the fight via 1st-round TKO.
On February 29, 2008 Jason Litzau fought Robert Guerrero in a featherweight world-title fight for Guerrero's IBF title. Litzau was 24 years old and with a record of 23-2 (19), and Guerrero was 24 years old and with a record of 21-1-1 (14). Litzau lost the fight via 8th-round KO.
On December 16, 2006 Jason Litzau faced off against Jose Andres Hernandez at age 23. He was coming in with a record of 20-1 (18). Litzau lost the fight via 8th-round KO.