Jamie McDonnell has three losses against three opponents on his boxing record. For a list of McDonnell's best fights, refer to "Best fights of Jamie McDonnell".
On May 25, 2018 Jamie McDonnell met Naoya Inoue in a bantamweight (WBA (Regular)) world-title defense fight. McDonnell was 32 years old and with a record of 29-3-1 (13), and Inoue was 25 years old and with a record of 15-0 (13). McDonnell lost the fight via 1st-round TKO and lost the title.
On March 28, 2008 Jamie McDonnell faced off against Lee Haskins at age 21. He was coming in with a record of 8-2-1 (2), and Haskins was 25 years old and with a record of 16-2 (9). McDonnell lost the fight via 8-round points decision.
On December 8, 2007 Jamie McDonnell faced off against Chris Edwards in a super-flyweight bout at age 21. He was coming in with a record of 8-1-1 (2). McDonnell lost the fight via 12-round split decision.