Israil Madrimov has two losses against two opponents on his boxing record. For a list of Madrimov's best fights, refer to "Best fights of Israil Madrimov".
On February 22, 2025 Israil Madrimov fought Vergil Ortiz Jr. in a super-welterweight world-title fight for Ortiz Jr.'s WBC title. Madrimov was 30 years old and with a record of 10-2-1 (7), and Ortiz Jr. was 26 years old and with a record of 22-0 (21). Madrimov lost the fight via 12-round unanimous decision.
On August 3, 2024 Israil Madrimov, the WBA champion, met Terence Crawford, the WBO champion, in a super-welterweight world-title unification fight. Madrimov was 29 years old and with a record of 10-1-1 (7), and Crawford was 36 years old and with a record of 40-0 (31). Madrimov lost the fight via 12-round unanimous decision and lost his title.