Isaac Lowe has three losses against three opponents on his boxing record. For a list of Lowe's best fights, refer to "Best fights of Isaac Lowe".
On December 21, 2024 Isaac Lowe faced off against Lee McGregor in a featherweight bout at age 30. He was coming in with a record of 25-3-3 (8), and McGregor was 27 years old and with a record of 14-1-1 (11). Lowe lost the fight via 10-round unanimous decision.
On April 23, 2022 Isaac Lowe faced off against Nick Ball in a featherweight bout at age 28. He was coming in with a record of 21-2-3 (6), and Ball was 25 years old and with a record of 14-0 (7). Lowe lost the fight via 6th-round TKO.
On December 3, 2021 Isaac Lowe faced off against Luis Alberto Lopez at age 27. He was coming in with a record of 21-1-3 (6), and Lopez was 28 years old and with a record of 23-2 (12). Lowe lost the fight via 7th-round KO.
