Erika Cruz has two losses against two opponents on her boxing record. For a list of Cruz's best fights, refer to "Best fights of Erika Cruz".
On February 4, 2023 Erika Cruz, the WBA champion, met Amanda Serrano, the WBC, IBF, WBO and The Ring champion, in a featherweight world-title unification fight. Cruz was 32 years old and with a record of 15-2 (3), and Serrano was 34 years old and with a record of 43-2-1 (30). Cruz lost the fight via 10-round unanimous decision and lost her title.
On June 25, 2016 Erika Cruz faced off against Alondra González Flores at age 26. She was coming in with a record of 1-1 (0). Cruz lost the fight via 4-round majority decision.