Edwin Rodríguez has three losses against three opponents on his boxing record. For a list of Rodríguez's best fights, refer to "Best fights of Edwin Rodríguez".
On July 20, 2024 Edwin Rodríguez faced off against Angel Barrientes in a super-middleweight bout at age 39. He was coming in with a record of 31-3 (19). Rodríguez lost the fight via 10-round unanimous decision.
On April 30, 2016 Edwin Rodríguez faced off against Thomas Williams Jr. in a super-middleweight bout at age 30. He was coming in with a record of 28-2 (18). Rodríguez lost the fight via 2nd-round TKO.
On November 16, 2013 Edwin Rodríguez faced off against Andre Ward in a super-middleweight bout at age 28. He was coming in with a record of 24-1 (15), and Ward was 29 years old and with a record of 26-0 (14). Rodríguez lost the fight via 12-round unanimous decision.
