Edward Vazquez has three losses against three opponents on his boxing record. For a list of Vazquez's best fights, refer to "Best fights of Edward Vazquez".
On May 4, 2025 Edward Vazquez fought Rafael Espinoza in a featherweight world-title fight for Espinoza's WBO title. Vazquez was 29 years old and with a record of 17-3 (4), and Espinoza was 31 years old and with a record of 26-0 (22). Vazquez lost the fight via 7th-round TKO.
On November 4, 2023 Edward Vazquez fought Joe Cordina in a super-featherweight world-title fight for Cordina's IBF title. Vazquez was 28 years old and with a record of 15-2 (3), and Cordina was 31 years old and with a record of 16-0 (9). Vazquez lost the fight via 12-round majority decision.
On February 5, 2022 Edward Vazquez faced off against Raymond Ford at age 26. He was coming in with a record of 11-1 (3), and Ford was 22 years old and with a record of 10-0-1 (6). Vazquez lost the fight via 10-round split decision.
