Dominic Breazeale has three losses against three opponents on his boxing record. For a list of Breazeale's best fights, refer to "Best fights of Dominic Breazeale".
On February 20, 2021 Dominic Breazeale faced off against Otto Wallin at age 35. He was coming in with a record of 20-3 (18), and Wallin was 30 years old and with a record of 21-1 (14). Breazeale lost the fight via 12-round unanimous decision.
On May 18, 2019 Dominic Breazeale fought Deontay Wilder in a heavyweight world-title fight for Wilder's WBC title. Breazeale was 33 years old and with a record of 20-2 (18), and Wilder was 33 years old and with a record of 40-0-1 (39). Breazeale lost the fight via 1st-round KO.
On June 25, 2016 Dominic Breazeale fought Anthony Joshua in a heavyweight world-title fight for Joshua's IBF title. Breazeale was 30 years old and with a record of 17-1 (15), and Joshua was 26 years old and with a record of 16-0 (16). Breazeale lost the fight via 7th-round TKO.