Here is a list of Mathews's best fights. For a list of Mathews's losses, refer to "Derry Mathews Losses".
On April 21, 2012 Derry Mathews faced off against Anthony Crolla in a lightweight bout at age 28. He was coming in with a record of 30-6-1 (16), and Crolla was 25 years old and with a record of 23-2 (9). Mathews stopped Anthony Crolla via TKO.
On July 13, 2013 Derry Mathews faced off against Tommy Coyle in a lightweight bout at age 29. He was coming in with a record of 33-8-2 (18), and Coyle was 23 years old and with a record of 15-1 (6). Mathews stopped Tommy Coyle via KO.
On May 10, 2014 Derry Mathews faced off against Martin Gethin in a lightweight bout at age 30. He was coming in with a record of 35-9-2 (19), and Gethin was 30 years old and with a record of 24-4-1 (11). Mathews won the fight via 12-round split decision.