Derrieck Cuevas has two losses against two opponents on his boxing record. For a list of Cuevas's best fights, refer to "Best fights of Derrieck Cuevas".
On March 29, 2025 Derrieck Cuevas fought Brian Norman Jr. in a welterweight world-title fight for Norman Jr.'s WBO title. Cuevas was 30 years old and with a record of 27-2-1 (19), and Norman Jr. was 24 years old and with a record of 26-0 (20). Cuevas lost the fight via 3rd-round TKO.
On December 4, 2020 Derrieck Cuevas faced off against Damian Ezequiel Bonelli at age 26. He was coming in with a record of 23-1-1 (15). Cuevas lost the fight via 6-round split decision.