David Lemieux has five losses against five opponents on his boxing record. For a list of Lemieux's best fights, refer to "Best fights of David Lemieux".
On May 21, 2022 David Lemieux faced off against David Benavidez in a super-middleweight bout at age 33. He was coming in with a record of 43-5 (36), and Benavidez was 25 years old and with a record of 25-0 (22). Lemieux lost the fight via 3rd-round TKO.
On December 16, 2017 David Lemieux fought Billy Joe Saunders in a middleweight world-title fight for Saunders' WBO title. Lemieux was 28 years old and with a record of 38-4 (33), and Saunders was 28 years old and with a record of 25-0 (12). Lemieux lost the fight via 12-round unanimous decision.
On October 17, 2015 David Lemieux, the IBF champion, met Gennady Golovkin, the WBA (Super) and WBC champion, in a middleweight world-title unification fight. Lemieux was 26 years old and with a record of 34-3 (31), and Golovkin was 33 years old and with a record of 33-0 (30). Lemieux lost the fight via 8th-round TKO and lost his title.
On December 10, 2011 David Lemieux faced off against Joachim Alcine in a middleweight bout at age 22. He was coming in with a record of 25-2 (24). Lemieux lost the fight via 12-round majority decision.
On April 8, 2011 David Lemieux faced off against Marco Antonio Rubio at age 22. He was coming in with a record of 25-1 (24), and Rubio was 30 years old and with a record of 49-5-1 (42). Lemieux lost the fight via 7th-round TKO.