Chris Arreola has seven losses against six opponents on his boxing record. For a list of Arreola's best fights, refer to "Best fights of Chris Arreola".
On May 1, 2021 Chris Arreola faced off against Andy Ruiz Jr. at age 40. He was coming in with a record of 38-7-1 (33), and Ruiz Jr. was 31 years old and with a record of 33-2 (22). Arreola lost the fight via 12-round unanimous decision.
On August 3, 2019 Chris Arreola faced off against Adam Kownacki at age 38. He was coming in with a record of 38-6-1 (33), and Kownacki was 30 years old and with a record of 19-0 (15). Arreola lost the fight via 12-round unanimous decision.
On July 16, 2016 Chris Arreola fought Deontay Wilder in a heavyweight world-title fight for Wilder's WBC title. Arreola was 35 years old and with a record of 36-5-1 (31), and Wilder was 30 years old and with a record of 36-0 (35). Arreola lost the fight via 8th-round retirement.
On May 10, 2014 Chris Arreola fought Bermane Stiverne in a heavyweight world-title fight for the WBC title. Arreola was 33 years old and with a record of 35-4 (31), and Stiverne was 35 years old and with a record of 23-1-1 (20). Arreola lost the fight via 6th-round TKO.
On April 27, 2013 Chris Arreola faced off against Bermane Stiverne in a heavyweight bout at age 32. He was coming in with a record of 34-3 (30), and Stiverne was 34 years old and with a record of 22-1-1 (20). Arreola lost the fight via 12-round unanimous decision.
On April 24, 2010 Chris Arreola faced off against Tomasz Adamek in a heavyweight bout at age 29. He was coming in with a record of 28-2 (25), and Adamek was 33 years old and with a record of 40-1 (27). Arreola lost the fight via 12-round majority decision.
On September 26, 2009 Chris Arreola fought Vitali Klitschko in a heavyweight world-title fight for Klitschko's WBC title. Arreola was 28 years old and with a record of 27-1 (24), and Klitschko was 38 years old and with a record of 37-2 (36). Arreola lost the fight via 10th-round retirement.
