Chazz Witherspoon has four losses against four opponents on his boxing record. For a list of Witherspoon's best fights, refer to "Best fights of Chazz Witherspoon".
On October 12, 2019 Chazz Witherspoon faced off against Oleksandr Usyk in a heavyweight bout at age 38. He was coming in with a record of 38-4 (29), and Usyk was 32 years old and with a record of 16-0 (12). Witherspoon lost the fight via 7th-round retirement.
On April 28, 2012 Chazz Witherspoon faced off against Seth Mitchell in a heavyweight bout at age 30. He was coming in with a record of 30-3 (22). Witherspoon lost the fight via 3rd-round TKO.
On December 15, 2009 Chazz Witherspoon faced off against Tony Thompson in a heavyweight bout at age 28. He was coming in with a record of 26-2 (18). Witherspoon lost the fight via 9th-round TKO.
On June 21, 2008 Chazz Witherspoon faced off against Chris Arreola in a heavyweight bout at age 26. He was coming in with a record of 23-1 (15), and Arreola was 27 years old and with a record of 23-0 (21). Witherspoon lost the fight via 3-round disqualification.
