Brian Nielsen has three losses against three opponents on his boxing record. For a list of Nielsen's best fights, refer to "Best fights of Brian Nielsen".
On May 7, 2011 Brian Nielsen faced off against Evander Holyfield at age 46. He was coming in with a record of 64-3 (43), and Holyfield was 48 years old and with a record of 43-10-2 (28). Nielsen lost the fight via 10th-round TKO.
On October 13, 2001 Brian Nielsen faced off against Mike Tyson at age 36. He was coming in with a record of 62-2 (43), and Tyson was 35 years old and with a record of 48-3 (42). Nielsen lost the fight via 6th-round retirement.
On June 18, 1999 Brian Nielsen faced off against Dicky Ryan at age 34. He was coming in with a record of 49-1 (33). Nielsen lost the fight via 10th-round TKO.
