Andre Dirrell has three losses against three opponents on his boxing record. For a list of Dirrell's best fights, refer to "Best fights of Andre Dirrell".
On March 3, 2018 Andre Dirrell met José Uzcátegui in a super-middleweight (IBF) world-title defense fight. Dirrell was 34 years old and with a record of 26-3 (16), and Uzcátegui was 27 years old and with a record of 26-2 (22). Dirrell lost the fight via 8th-round retirement and lost the title.
On May 23, 2015 Andre Dirrell fought James DeGale in a super-middleweight world-title fight for the IBF title. Dirrell was 31 years old and with a record of 24-2 (16), and DeGale was 29 years old and with a record of 20-1 (14). Dirrell lost the fight via 12-round unanimous decision.
On October 17, 2009 Andre Dirrell fought Carl Froch in a super-middleweight world-title fight for Froch's WBC title. Dirrell was 26 years old and with a record of 18-1 (13), and Froch was 32 years old and with a record of 25-0 (20). Dirrell lost the fight via 12-round split decision.