Gianluca Branco has three losses against three opponents on his boxing record. For a list of Branco's best fights, refer to "Best fights of Gianluca Branco".
On March 26, 2010 Gianluca Branco faced off against Matthew Hatton in a welterweight bout at age 39. He was coming in with a record of 43-3-1 (22), and Hatton was 28 years old and with a record of 38-4-2 (15). Branco lost the fight via 12-round unanimous decision.
On March 4, 2006 Gianluca Branco fought Miguel Cotto in a super-lightweight world-title fight for Cotto's WBO title. Branco was 35 years old and with a record of 36-2-1 (19), and Cotto was 25 years old and with a record of 25-0 (21). Branco lost the fight via 8th-round TKO.
On January 24, 2004 Gianluca Branco fought Arturo Gatti in a super-lightweight world-title fight for the WBC title. Branco was 33 years old and with a record of 32-1-1 (15), and Gatti was 31 years old and with a record of 36-6 (28). Branco lost the fight via 12-round unanimous decision.