Angel Manfredy has eight losses against eight opponents on his boxing record. For a list of Manfredy's best fights, refer to "Best fights of Angel Manfredy".
On April 16, 2004 Angel Manfredy faced off against Craig Weber at age 29. He was coming in with a record of 43-8-1 (32). Manfredy lost the fight via 10-round unanimous decision.
On July 29, 2003 Angel Manfredy faced off against Courtney Burton at age 28. He was coming in with a record of 42-7-1 (31). Manfredy lost the fight via 8th-round KO.
On March 9, 2002 Angel Manfredy fought Paul Spadafora in a lightweight world-title fight for Spadafora's IBF title. Manfredy was 27 years old and with a record of 39-6-1 (29), and Spadafora was 26 years old and with a record of 34-0 (14). Manfredy lost the fight via 12-round unanimous decision.
On September 2, 2000 Angel Manfredy fought Diego Corrales in a super-featherweight world-title fight for Corrales' IBF title. Manfredy was 25 years old and with a record of 33-5-1 (26), and Corrales was 23 years old and with a record of 32-0 (26). Manfredy lost the fight via 3rd-round TKO.
On August 14, 1999 Angel Manfredy fought Stevie Johnston in a lightweight world-title fight for Johnston's WBC title. Manfredy was 24 years old and with a record of 28-4-1 (22). Manfredy lost the fight via 12-round unanimous decision.
On December 19, 1998 Angel Manfredy fought Floyd Mayweather Jr. in a super-featherweight world-title fight for Mayweather Jr.'s WBC title. Manfredy was 24 years old and with a record of 25-3-1 (20), and Mayweather Jr. was 21 years old and with a record of 18-0 (14). Manfredy lost the fight via 2nd-round TKO.
On May 26, 1994 Angel Manfredy faced off against Jeff Mason at age 19. He was coming in with a record of 2-2-1 (2). Manfredy lost the fight via 4-round majority decision.
On June 10, 1993 Angel Manfredy faced off against Charles McClellan at age 18. He was coming in with a record of 0-1 (0). Manfredy lost the fight via 2nd-round TKO.