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Otis Griffin had 44 fights with 10 KO wins. Some of his best fights among these have been against Jeff Lacy, Byron Mitchell, Brock Stodden, Mike Nevitt, and Ernesto Castaneda. The following are Griffin's top 10 fights.
On Otis Griffin lost to Jeff Lacy via 10 round majority decision. Griffin was 31 years old with a record of 19-5-2 (7 KOs). Lacy was 31 years old with a record of 24-2 (17 KOs). Despite the loss, Griffin put on a good fight. The performance in this fight is the number one among all of Griffin's fights.
On Otis Griffin defeated Byron Mitchell via 8th round TKO. Griffin was 32 years old with a record of 22-6-2 (9 KOs). This fight is the second best performance in Griffin's career.
On Otis Griffin defeated Brock Stodden via 3rd round TKO. Griffin was 29 years old with a record of 18-1-2 (7 KOs).
On Otis Griffin defeated Mike Nevitt via 7th round TKO. Griffin was 29 years old with a record of 17-1-2 (6 KOs).
On Otis Griffin defeated Ernesto Castaneda in the rematch via 6th round KO. Griffin was 32 years old with a record of 20-6-2 (8 KOs).
On Otis Griffin defeated Matt Gockel via 1st round TKO. Griffin was 28 years old with a record of 11-1-2 (5 KOs).
On Otis Griffin defeated Adam Collins via 2nd round TKO. Griffin was 35 years old with a record of 24-10-2 (10 KOs).
On Otis Griffin defeated Doug Lilly via 1st round KO. Griffin was 27 years old with a record of 6-1-1 (4 KOs).
On Otis Griffin defeated JJ McAllister via 2nd round TKO. Griffin was 27 years old with a record of 5-1-1 (3 KOs).
On Otis Griffin defeated James Sundin via 2nd round TKO. Griffin was 26 years old with a record of 4-1-1 (2 KOs).