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Darren Barker had a total of two losses in his professional boxing career — both of them in title bouts. He suffered his first loss against Sergio Martínez via 11th round KO on October 1, 2011, which ended his 23-fight win streak. Both of Barker's losses came via stoppage.
Felix Sturm and Sergio Martínez are the two boxers who have beaten Barker.
This is the first loss in Darren Barker's career. Barker lost to Argentinian boxer Sergio Martínez via 11th round KO on . He was fighting for Martínez' middleweight The Ring title, he was 29 years old with a record of 23-0. Martínez was 36 years old with a record of 47-2-2.
On Barker lost to German boxer Felix Sturm via 2nd round TKO. He was defending his middleweight IBF title, he was 31 years old with a record of 26-1. Sturm was 34 years old with a record of 38-4-2.