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Francois Botha had a total of 11 losses in his professional boxing career — three of them in title bouts and eight in non-title bouts. He suffered his first loss against Michael Moorer via 12th round TKO on November 9, 1996, which ended his 35-fight win streak. He has been stopped nine times and lost two times via decision.
Andrzej Wawrzyk, Joseph Parker, Sonny Bill Williams, Francesco Pianeta, and Carlos Takam are some of the boxers who have beaten Botha.
This is the first loss in Francois Botha's career. Botha lost to American boxer Michael Moorer via 12th round TKO on . He was fighting for Moorer's heavyweight IBF title, he was 28 years old with a record of 35-0. Moorer was also 28 years old, with a record of 37-1.
On Botha lost to American boxer Mike Tyson via 5th round KO in a non-title bout. He was 30 years old with a record of 39-1. Tyson was 32 years old with a record of 45-3.
On Botha lost to British boxer Lennox Lewis via 2nd round TKO. He was fighting for Lewis' heavyweight WBC and IBF titles, he was 31 years old with a record of 40-2-1. Lewis was 34 years old with a record of 36-1-1.
On Botha lost to Ukrainian boxer Wladimir Klitschko via 8th round TKO. He was fighting for Klitschko's heavyweight WBO title, he was 33 years old with a record of 44-3-1. Klitschko was 25 years old with a record of 37-1.
On Botha lost to American boxer Evander Holyfield via 8th round TKO in a non-title bout. He was 41 years old with a record of 47-4-3. Holyfield was 47 years old with a record of 42-10-2.
On Botha lost to American boxer Michael Grant via 12th round KO in a non-title bout. He was 43 years old with a record of 48-5-3. Grant was 39 years old with a record of 47-4.
On Botha lost to French boxer Carlos Takam via 11th round TKO in a non-title bout. He was 43 years old with a record of 48-6-3. Takam was 31 years old with a record of 24-1.
On Botha lost to Francesco Pianeta via 10 round unanimous decision in a non-title bout. He was 43 years old with a record of 48-7-3.
On Botha lost to Sonny Bill Williams via 10 round unanimous decision in a non-title bout. He was 44 years old with a record of 48-8-3.
On Botha lost to New Zealander boxer Joseph Parker via 2nd round TKO in a non-title bout. He was 44 years old with a record of 48-9-3. Parker was 21 years old with a record of 5-0.
On Botha lost to Andrzej Wawrzyk via 5th round TKO in a non-title bout. He was 45 years old with a record of 48-10-3.